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All open SBIR and STTR grant topics

This page lists all SBIR and STTR opportunities that are open now. The agencies are DoD, NSF, USDA, the Department of Energy, and NIH. The data comes from the official sources, DSIP and Grants.gov. The list is sorted by deadline.

Most topics need more than one company can give. A topic can need a lab, a clearance, or a technology that one company does not have. For this reason, every topic on this page has a team list.

Applying is always free.
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3

Join or build a team

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Apply on the official site

Open opportunities

30 topics and solicitations. Each one is open for proposals.

USDA-NIFA
Open

Small Business Innovation Research and Small Business Technology Transfer Programs Phase II

Topic #: USDA-NIFA-SBIR-012221
Deadline

11/17/2026

Closes in 7 days
DOE-ARPAE
Open

Unlocking New Levels of Output and Capacity for Key Subsurface Resources SBIR/STTR (UNLOCK SBIR/STTR)

Topic #: DE-FOA-0003631
Deadline

11/20/2026

Closes in 10 days
NAVY
Open

ONR Open Topic for Low-Cost Heads Up Displays (HUDs) for Virtual & Augmented Reality (VR/AR)

Topic #: DON27BX01-NP001
Deadline

11/25/2026

USAF
Open

Reusable Illumination System

Topic #: DAF27BZ01-DV007
Deadline

11/25/2026

USAF
Open

Technical Data Package Modernization for Information Assurance and Secure Data Exchange

Topic #: DAF27BZ01-DV008
Deadline

11/25/2026

USAF
Open

US Production of Ultra-High Temperature Ceramic-Yielding Preceramic Polymers

Topic #: DAF27BZ01-DV009
Deadline

11/25/2026

USAF
Open

Low SWaP, 2-micron Fiber Amplifiers

Topic #: DAF27BZ01-DV010
Deadline

11/25/2026

USAF
Open

Agile Wire Harness Manipulation and Installation for Unmanned Aerial Systems

Topic #: DAF27BZ01-DV011
Deadline

11/25/2026

USAF
Open

Agile Autonomous Technical Data Package to Path Robotic Task Specification

Topic #: DAF27BZ01-DV012
Deadline

11/25/2026

USAF
Open

Advanced Reserve Power Source Technologies

Topic #: DAF27BZ01-DV013
Deadline

11/25/2026

USAF
Open

Shallow Jet Spurt Engineering Model

Topic #: DAF27BZ01-NV001
Deadline

11/25/2026

USAF
Open

Optimally Packaged Assembly for Laser Systems (OPALS)

Topic #: DAF27BZ01-NV002
Deadline

11/25/2026

USAF
Open

Multiple Telemetry Site Signal Source Synchronization

Topic #: DAF27BZ01-NV003
Deadline

11/25/2026

USAF
Open

Long Rod Delivery System

Topic #: DAF27BZ01-NV004
Deadline

11/25/2026

USAF
Open

Luminescence-Based Surface Measurement Technique for Simultaneous Pressure and Temperature Measurements within Non-Oxygen Based Hypersonic Ground Test Facilities

Topic #: DAF27BZ01-NV005
Deadline

11/25/2026

USAF
Open

High Speed, Low Temperature Hyperspectral Imager for High Enthalpy Ground Testing

Topic #: DAF27BZ01-NV006
Deadline

11/25/2026

NAVY
Open

Cleaner for the Time Domain Reflectometer Tank Level Indicator

Topic #: DON27BZ01-NV001
Deadline

11/25/2026

NAVY
Open

Fire Resistant Joiner Bulkhead

Topic #: DON27BZ01-NV002
Deadline

11/25/2026

NAVY
Open

Input-Output Unit (IOU) for Secure Processing and Routing of Hull, Mechanical, & Electrical (HM&E) and Navigation Signals

Topic #: DON27BZ01-NV004
Deadline

11/25/2026

OSD
Open

Counter-Unmanned Aerial Systems Rapid Maturation

Topic #: OSW27BZ01-DV002
Deadline

11/25/2026

OSD
Open

Counter-Unmanned Aerial Systems Rapid Maturation

Topic #: OSW27BZ01-NV001
Deadline

11/25/2026

USAF
Open

AI-Enabled Computed Vision Air-to-Air Refueling Performance Assessment and Automated Pilot Debrief System

Topic #: DAF27TZ01-DV001
Deadline

11/25/2026

USAF
Open

Cyber Resiliency for Fog and Edge Computing Devices

Topic #: DAF27TZ01-DV002
Deadline

11/25/2026

USAF
Open

Fusion of Cooperative Information Sharing for Uncrewed Air Systems (FOCISAUS)

Topic #: DAF27TZ01-DV003
Deadline

11/25/2026

DARPA
Open

TRIAGE-X: Autonomous Casualty Triage and Treatment in Chemically Contaminated Mass Casualty Events

Topic #: DPA26BZ06-DV028
Deadline

11/25/2026

NSF
Open

NSF Small Business Innovation Research / Small Business Technology Transfer Phase I, Phase II, Fast-Track Programs: A Pilot Emphasis on Scientific Instrumentation

Topic #: 26-511
Deadline

03/04/2027

NIH
Open

NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)

Topic #: PA-27-100
Deadline

04/05/2027

NIH
Open

NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)

Topic #: PA-27-102
Deadline

04/05/2027

NIH
Open

NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)

Topic #: PA-27-101
Deadline

04/05/2029

NIH
Open

SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)

Topic #: PAR-27-098
Deadline

04/05/2029

DOD SBIR/STTR Requirements:

1. DSIP account: Create an account on the Defense SBIR/STTR Innovation Portal (DSIP).

2. SAM registration: Keep an active registration in the System for Award Management (SAM).

3. UEI: You need a valid Unique Entity ID (UEI) from SAM.gov.

4. Company Requirements:

  • Your company must be a small business with 500 or fewer employees.
  • Your company must be owned and operated in the United States.
  • The Principal Investigator must work mainly for your company.

For more information, see the DoD SBIR/STTR website.